I-125 Labeled PACAP38 is a specialized radioligand designed for precise receptor binding assays. It enables detailed study of PACAP38 interactions with PAC1 and other VPAC receptors, supporting research in neuroprotection, neurodevelopment, nociception, and inflammation. This high-affinity product (Kd = 100 pM) offers rapid and saturable membrane binding, making it ideal for investigating diverse physiological functions and potential therapeutic implications in conditions like migraines.